Dirk M Hermann Selected Research

Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)

1/2022	Tenascin-C restricts reactive astrogliosis in the ischemic brain.
1/2022	N-Methyl-D-Aspartate Receptors Antagonist Prevents Secondary Ischemic Brain Injury Associated With Lipopolysaccharide-Induced Sepsis-Like State Presumably via Immunomodulatory Actions.
1/2022	Phosphodiesterase 10A Is a Critical Target for Neuroprotection in a Mouse Model of Ischemic Stroke.
1/2021	Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration.
10/2020	Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia.
1/2020	Neuroprotection Induced by Energy and Protein-Energy Undernutrition Is Phase-Dependent After Focal Cerebral Ischemia in Mice.
9/2019	Preclinical concepts and results with the GABAA antagonist S44819 in a mouse model of middle cerebral artery occlusion.
1/2019	Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes.
3/2017	Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways.
11/2016	Systemic Proteasome Inhibition Induces Sustained Post-stroke Neurological Recovery and Neuroprotection via Mechanisms Involving Reversal of Peripheral Immunosuppression and Preservation of Blood-Brain-Barrier Integrity.

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Dirk M Hermann Research Topics

Disease

94	Stroke (Strokes) 01/2022 - 11/2002
49	Brain Ischemia (Cerebral Ischemia) 01/2022 - 03/2004
43	Ischemic Stroke 01/2022 - 11/2004
30	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022 - 01/2005
29	Infarction (Infarctions) 01/2022 - 03/2004
27	Brain Injuries (Brain Injury) 01/2022 - 03/2004
26	Ischemia 01/2022 - 11/2002
13	Brain Edema (Cerebral Edema) 01/2022 - 01/2005
13	Inflammation (Inflammations) 01/2021 - 10/2006
10	Hypoxia (Hypoxemia) 01/2022 - 10/2007
8	Alzheimer Disease (Alzheimer's Disease) 10/2020 - 08/2011
5	Gliosis 01/2022 - 08/2009
5	Brain Infarction 04/2021 - 10/2015
4	Neuroinflammatory Diseases 01/2022 - 01/2020
4	Atrophy 01/2021 - 06/2014
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 11/2006
4	Atherosclerosis 12/2019 - 02/2003
4	Hyperlipidemias (Hyperlipidemia) 10/2015 - 11/2011
3	Sepsis (Septicemia) 01/2022 - 01/2020
3	Wounds and Injuries (Trauma) 01/2021 - 10/2012
3	Thrombosis (Thrombus) 01/2021 - 01/2013
3	Myocardial Infarction 01/2021 - 01/2013
3	Neoplasms (Cancer) 01/2021 - 11/2004
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 08/2013
3	Chronic Renal Insufficiency 11/2017 - 03/2014
3	Reperfusion Injury 10/2015 - 07/2007
3	Edema (Dropsy) 01/2013 - 11/2011
2	Multiple Sclerosis 01/2022 - 01/2020
2	Infections 01/2021 - 08/2015
2	Hemorrhage 01/2021 - 01/2013
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 01/2012
2	Hypertension (High Blood Pressure) 01/2021 - 12/2019
2	Hypotension (Low Blood Pressure) 01/2020 - 04/2013
2	Coronary Disease (Coronary Heart Disease) 01/2020 - 02/2003
2	Malnutrition (Nutritional Deficiencies) 01/2020 - 12/2019
2	Body Weight (Weight, Body) 01/2020 - 08/2015

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2002
11	Oxygen (Dioxygen)IBA 01/2022 - 02/2003
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2005
10	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 06/2006
8	AntioxidantsIBA 01/2022 - 11/2004
8	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021 - 11/2006
8	Caspase 3 (Caspase-3)IBA 01/2019 - 04/2004
8	MelatoninIBA 10/2015 - 03/2002
8	Tissue Plasminogen Activator (Alteplase)FDA Link 11/2012 - 03/2004
7	Pharmaceutical PreparationsIBA 01/2021 - 01/2008
7	oxidized low density lipoproteinIBA 01/2019 - 09/2012
7	Erythropoietin FDA Link 01/2011 - 02/2005
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 01/2005
5	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 01/2008
4	S44819IBA 02/2020 - 10/2018
4	Adenosine Triphosphate (ATP)IBA 01/2020 - 10/2008
4	Neuroprotective AgentsIBA 01/2020 - 01/2005
4	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 01/2020 - 01/2005
4	Proteasome InhibitorsIBA 11/2016 - 11/2012
4	Apolipoproteins E (ApoE)IBA 10/2015 - 10/2006
4	cresyl violetIBA 05/2010 - 11/2002
3	LipopolysaccharidesIBA 01/2022 - 01/2020
3	Biomarkers (Surrogate Marker)IBA 09/2021 - 01/2017
3	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 12/2019
3	Nitric Oxide Synthase (NO Synthase)IBA 01/2021 - 02/2005
3	LithiumIBA 01/2021 - 03/2017
3	Evans Blue (Blue, Evans)FDA Link 01/2021 - 11/2004
3	CytokinesIBA 01/2021 - 12/2007
3	Tight Junction ProteinsIBA 12/2020 - 11/2011
3	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 10/2020 - 01/2019
3	CeramidesIBA 10/2020 - 01/2019
3	InterferonsIBA 07/2020 - 11/2014
3	Biological ProductsIBA 01/2020 - 03/2012
3	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2018 - 06/2012
3	Amyloid (Amyloid Fibrils)IBA 11/2017 - 01/2016
3	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2017 - 11/2013
3	BSc2118IBA 11/2016 - 11/2012
3	Immunoglobulin G (IgG)IBA 10/2015 - 11/2011
3	CholesterolIBA 10/2015 - 11/2011
3	ApolipoproteinsIBA 06/2012 - 10/2006
3	Phosphotransferases (Kinase)IBA 03/2012 - 09/2005
3	indoleIBA 09/2005 - 11/2004
2	AntigensIBA 01/2022 - 01/2021
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 04/2021 - 10/2018
2	AntibodiesIBA 01/2021 - 05/2010
2	salicylhydroxamic acid (SHAM)IBA 01/2021 - 10/2006
2	MicroRNAs (MicroRNA)IBA 01/2021 - 08/2013
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 11/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 12/2010
2	Antidepressive Agents (Antidepressants)IBA 01/2020 - 09/2016
2	Messenger RNA (mRNA)IBA 01/2020 - 08/2009
2	LipidsIBA 01/2020 - 01/2011
2	SphingolipidsIBA 01/2019 - 01/2019
2	AcidsIBA 01/2019 - 01/2019
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2019 - 11/2011
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 01/2012

Therapy/Procedure

41	Therapeutics 01/2022 - 04/2006
13	Transplantation 11/2021 - 08/2009
3	Injections 11/2016 - 01/2005
3	Lasers (Laser) 10/2015 - 04/2004
3	Axotomy 07/2008 - 02/2005
2	Ligation 01/2022 - 01/2022
2	Transcranial Magnetic Stimulation 01/2020 - 01/2019
2	Electrodes (Electrode) 01/2020 - 10/2006